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Showing posts with label alcohol. Show all posts
Showing posts with label alcohol. Show all posts

Thursday, November 3, 2011

Swede shocked by backyard elk 'threesome'


the best part of this article is how its written in a scandalous tone....Thanks to Alberto A for the link - MA

From the local.se

A man in western Sweden was greeted by an unusual sight on Wednesday morning when he saw three elk engaged in what appeared to be group sex in his backyard.

“I had just gone out on the balcony to get some fresh air,” Peter Lundgren, a 43-year-old marketing manager from Lindome, south of Gothenburg, told The Local.

“They were eating apples and then suddenly they assumed the position.”

Lundgren quickly grabbed his camera to document the young male elk mounting an older female elk which in turn appeared to be sniffing or licking the rear end of another young male elk.

He explained that elk are a common sight in his neighbourhood, as the large beasts frequently roam from nearby wooded areas through people's yards.

While he's used to seeing elk get tipsy from eating fermented apples, Lundgren said he was wholly unprepared to have a front row seat at an elk sex show taking place in his backyard.

“I'd never seen anything like it. Not with elk, at least,” he said.

Pär Grängstedt, a researcher at the Grimsö research station in central Sweden, confirmed that it's “extremely rare” to see elk exhibit mating behaviour in a residential area.

“As elk live in the woods, they usually mate in the woods,” he said.

The attempted elk intercourse witnessed by Lundgren is all the more unusual, according to Grängstedt, because the elk mating season ended in early October.

He added, however, that it's not unusual for elk to have sex while others look on.

“Usually there are several males in the area competing to be with the in-heat female. The strongest one usually wins, and the others are left to watch,” he said.

“It's quite normal behaviour.”

While Lundgren explained that it didn't appear the frisky young male elk was able to fully consummate his mating attempt with the older female, Grängstedt said there can be little doubt about his intentions.

“Elk don't mount one another just for the heck of it like some other animals,” he said.

Grängstedt theorized that the young male may have been rebuffed due to a lack of experience, choosing both the wrong time and place to fulfill his lustful desires.

“An older bull would never try to mount a cow in a wide-open residential backyard at this time of year,” he said.

Wednesday, October 12, 2011

culture more then consumption determines reaction to alcohol


Thanks to Geraldine F for the link
from the BBC
by Kate Fox
Viewpoint: Is the alcohol message all wrong?
Many people think heavy drinking causes promiscuity, violence and anti-social behaviour. That's not necessarily true, argues Kate Fox.

I am a social anthropologist, but what I do is not the traditional intrepid sort of anthropology where you go and study strange tribes in places with mud huts and monsoons and malaria.

I really don't see why anthropologists feel they have to travel to unpronounceable corners of the world in order to study strange tribal cultures with bizarre beliefs and mysterious customs, when in fact the weirdest and most puzzling tribe of all is right here on our doorstep. I am of course talking about my own native culture - the British.

And if you want examples of bizarre beliefs and weird customs, you need look no further than our attitude to drinking and our drinking habits. Pick up any newspaper and you will read that we are a nation of loutish binge-drinkers - that we drink too much, too young, too fast - and that it makes us violent, promiscuous, anti-social and generally obnoxious.

Clearly, we Brits do have a bit of a problem with alcohol, but why?

The problem is that we Brits believe that alcohol has magical powers - that it causes us to shed our inhibitions and become aggressive, promiscuous, disorderly and even violent.

But we are wrong.

In high doses, alcohol impairs our reaction times, muscle control, co-ordination, short-term memory, perceptual field, cognitive abilities and ability to speak clearly. But it does not cause us selectively to break specific social rules. It does not cause us to say, "Oi, what you lookin' at?" and start punching each other. Nor does it cause us to say, "Hey babe, fancy a shag?" and start groping each other.

The effects of alcohol on behaviour are determined by cultural rules and norms, not by the chemical actions of ethanol.

There is enormous cross-cultural variation in the way people behave when they drink alcohol. There are some societies (such as the UK, the US, Australia and parts of Scandinavia) that anthropologists call "ambivalent" drinking-cultures, where drinking is associated with disinhibition, aggression, promiscuity, violence and anti-social behaviour.

There are other societies (such as Latin and Mediterranean cultures in particular, but in fact the vast majority of cultures), where drinking is not associated with these undesirable behaviours - cultures where alcohol is just a morally neutral, normal, integral part of ordinary, everyday life - about on a par with, say, coffee or tea. These are known as "integrated" drinking cultures.

This variation cannot be attributed to different levels of consumption - most integrated drinking cultures have significantly higher per-capita alcohol consumption than the ambivalent drinking cultures.

Instead the variation is clearly related to different cultural beliefs about alcohol, different expectations about the effects of alcohol, and different social rules about drunken comportment.

This basic fact has been proved time and again, not just in qualitative cross-cultural research, but also in carefully controlled scientific experiments - double-blind, placebos and all. To put it very simply, the experiments show that when people think they are drinking alcohol, they behave according to their cultural beliefs about the behavioural effects of alcohol.

The British and other ambivalent drinking cultures believe that alcohol is a disinhibitor, and specifically that it makes people amorous or aggressive, so when in these experiments we are given what we think are alcoholic drinks - but are in fact non-alcoholic "placebos" - we shed our inhibitions.

We become more outspoken, more physically demonstrative, more flirtatious, and, given enough provocation, some (young males in particular) become aggressive. Quite specifically, those who most strongly believe that alcohol causes aggression are the most likely to become aggressive when they think that they have consumed alcohol.

Our beliefs about the effects of alcohol act as self-fulfilling prophecies - if you firmly believe and expect that booze will make you aggressive, then it will do exactly that. In fact, you will be able to get roaring drunk on a non-alcoholic placebo.

And our erroneous beliefs provide the perfect excuse for anti-social behaviour. If alcohol "causes" bad behaviour, then you are not responsible for your bad behaviour. You can blame the booze - "it was the drink talking", "I was not myself" and so on.

But it is possible to change our drinking culture. Cultural shifts happen all the time, and there is extensive evidence (again from carefully controlled experiments, conducted in natural settings such as bars and nightclubs) to show that it doesn't take much to effect dramatic changes in how people behave when they drink.

These experiments show that even when people are very drunk, if they are given an incentive (either financial reward or even just social approval) they are perfectly capable of remaining in complete control of their behaviour - of behaving as though they were totally sober.

To achieve these changes, we need a complete and radical re-think of the aims and messages of all alcohol-education campaigns. So far, these efforts have perpetuated or even exacerbated the problem, because almost all of them simply reinforce our beliefs about the magical disinhibiting powers of alcohol.

The drinkaware website, for example, warns young people that a mere three pints of beer (ie a perfectly normal evening out) "can lead to anti-social, aggressive and violent behaviour", that "you might start saying things you don't mean and behaving out of character", that alcohol is implicated in a high percentage of sexual offences and street crimes, and that the morning after "you may wonder what you did the night before".

I would like to see a complete change of focus, with all alcohol-education and awareness campaigns designed specifically to challenge these beliefs - to get across the message that a) alcohol does not cause disinhibition (aggressive, sexual or otherwise) and that b) even when you are drunk, you are in control of and have total responsibility for your actions and behaviour.

Alcohol education will have achieved its ultimate goal not when young people in this country are afraid of alcohol and avoid it because it is toxic and dangerous, but when they are frankly just a little bit bored by it, when they don't need to be told not to binge-drink vodka shots, any more than they now need to be told not to swig down 15 double espressos in quick succession.

Even the silliest teenagers would not dream of doing that. And not because they have been educated about the dangers of a caffeine overdose - although there undoubtedly are such dangers - but because it would just be daft, what would be the point?

What we should be aiming for is a culture where you don't need alcohol-education programmes, any more than we now need coffee or tea education programmes.

If I were given total power, I could very easily engineer a nation in which coffee would become a huge social problem - a nation in which young people would binge-drink coffee every Friday and Saturday night and then rampage around town centres being anti-social, getting into fights and having unprotected sex in random one-night stands.

I would restrict access to coffee, thus immediately giving it highly desirable forbidden-fruit status. Then I would issue lots of dire warnings about the dangerously disinhibiting effects of coffee.

I would make sure everyone knew that even a mere three cups (six "units") of coffee "can lead to anti-social, aggressive and violent behaviour", and sexual promiscuity, thus instantly giving young people a powerful motive to binge-drink double espressos, and a perfect excuse to behave very badly after doing so.

I could legitimately base many of my scary coffee-awareness warnings on the known effects of caffeine, and I could easily make these sound like a recipe for disaster, or at least for disinhibition and public disorder.

It would not take long for my dire warnings to create the beliefs and expectations that would make them self-fulfilling prophecies. This may sound like a science fiction story, but it is precisely what our misguided alcohol-education programmes have done.

Over the past few decades the government, the drinks industry and schools have done exactly the opposite of what they should do to tackle our dysfunctional drinking. I remain perhaps stupidly optimistic that eventually they will find the courage to turn things around and start heading in the right direction.

Saturday, September 3, 2011

Is there a cure for alcohol hangovers? (from the NewYorker)

From the New Yorker
Is there any hope for the hung over?
by Joan Acocella


Of the miseries regularly inflicted on humankind, some are so minor and yet, while they last, so painful that one wonders how, after all this time, a remedy cannot have been found. If scientists do not have a cure for cancer, that makes sense. But the common cold, the menstrual cramp? The hangover is another condition of this kind. It is a preventable malady: don’t drink. Nevertheless, people throughout time have found what seemed to them good reason for recourse to alcohol. One attraction is alcohol’s power to disinhibit—to allow us, at last, to tell off our neighbor or make an improper suggestion to his wife. Alcohol may also persuade us that we have found the truth about life, a comforting experience rarely available in the sober hour. Through the lens of alcohol, the world seems nicer. (“I drink to make other people interesting,” the theatre critic George Jean Nathan used to say.) For all these reasons, drinking cheers people up. See Proverbs 31:6-7: “Give . . . wine unto those that be of heavy hearts. Let him drink, and forget his poverty, and remember his misery no more.” It works, but then, in the morning, a new misery presents itself.

A hangover peaks when alcohol that has been poured into the body is finally eliminated from it—that is, when the blood-alcohol level returns to zero. The toxin is now gone, but the damage it has done is not. By fairly common consent, a hangover will involve some combination of headache, upset stomach, thirst, food aversion, nausea, diarrhea, tremulousness, fatigue, and a general feeling of wretchedness. Scientists haven’t yet found all the reasons for this network of woes, but they have proposed various causes. One is withdrawal, which would bring on the tremors and also sweating. A second factor may be dehydration. Alcohol interferes with the secretion of the hormone that inhibits urination. Hence the heavy traffic to the rest rooms at bars and parties. The resulting dehydration seems to trigger the thirst and lethargy. While that is going on, the alcohol may also be inducing hypoglycemia (low blood sugar), which converts into light-headedness and muscle weakness, the feeling that one’s bones have turned to jello. Meanwhile, the body, to break down the alcohol, is releasing chemicals that may be more toxic than alcohol itself; these would result in nausea and other symptoms. Finally, the alcohol has produced inflammation, which in turn causes the white blood cells to flood the bloodstream with molecules called cytokines. Apparently, cytokines are the source of the aches and pains and lethargy that, when our bodies are attacked by a flu virus—and likewise, perhaps, by alcohol—encourage us to stay in bed rather than go to work, thereby freeing up the body’s energy for use by the white cells in combatting the invader. In a series of experiments, mice that were given a cytokine inducer underwent dramatic changes. Adult males wouldn’t socialize with young males new to their cage. Mothers displayed “impaired nest-building.” Many people will know how these mice felt.

But hangover symptoms are not just physical; they are cognitive as well. People with hangovers show delayed reaction times and difficulties with attention, concentration, and visual-spatial perception. A group of airplane pilots given simulated flight tests after a night’s drinking put in substandard performances. Similarly, automobile drivers, the morning after, get low marks on simulated road tests. Needless to say, this is a hazard, and not just for those at the wheel. There are laws against drunk driving, but not against driving with a hangover.

Hangovers also have an emotional component. Kingsley Amis, who was, in his own words, one of the foremost drunks of his time, and who wrote three books on drinking, described this phenomenon as “the metaphysical hangover”: “When that ineffable compound of depression, sadness (these two are not the same), anxiety, self-hatred, sense of failure and fear for the future begins to steal over you, start telling yourself that what you have is a hangover. . . . You have not suffered a minor brain lesion, you are not all that bad at your job, your family and friends are not leagued in a conspiracy of barely maintained silence about what a shit you are, you have not come at last to see life as it really is.” Some people are unable to convince themselves of this. Amis described the opening of Kafka’s “Metamorphosis,” with the hero discovering that he has been changed into a bug, as the best literary representation of a hangover.

The severity of a hangover depends, of course, on how much you drank the night before, but that is not the only determinant. What, besides alcohol, did you consume at that party? If you took other drugs as well, your hangover may be worse. And what kind of alcohol did you drink? In general, darker drinks, such as red wine and whiskey, have higher levels of congeners—impurities produced by the fermentation process, or added to enhance flavor—than do light-colored drinks such as white wine, gin, and vodka. The greater the congener content, the uglier the morning. Then there are your own characteristics—for example, your drinking pattern. Unjustly, habitually heavy drinkers seem to have milder hangovers. Your sex is also important. A woman who matches drinks with a man is going to get drunk faster than he, partly because she has less body water than he does, and less of the enzyme alcohol dehydrogenase, which breaks down alcohol. Apparently, your genes also have a vote, as does your gene pool. Almost forty per cent of East Asians have a variant, less efficient form of aldehyde dehydrogenase, another enzyme necessary for alcohol processing. Therefore, they start showing signs of trouble after just a few sips—they flush dramatically—and they get drunk fast. This is an inconvenience for some Japanese and Korean businessmen. They feel that they should drink with their Western colleagues. Then they crash to the floor and have to make awkward phone calls in the morning.

Hangovers are probably as old as alcohol use, which dates back to the Stone Age. Some anthropologists have proposed that alcohol production may have predated agriculture; in any case, it no doubt stimulated that development, because in many parts of the world the cereal harvest was largely given over to beer-making. Other prehistorians have speculated that alcohol intoxication may have been one of the baffling phenomena, like storms, dreams, and death, that propelled early societies toward organized religion. The ancient Egyptians, who, we are told, made seventeen varieties of beer, believed that their god Osiris invented this agreeable beverage. They buried their dead with supplies of beer for use in the afterlife.

Alcohol was also one of our ancestors’ foremost medicines. Berton Roueché, in a 1960 article on alcohol for The New Yorker, quoted a prominent fifteenth-century German physician, Hieronymus Brunschwig, on the range of physical ills curable by brandy: head sores, pallor, baldness, deafness, lethargy, toothache, mouth cankers, bad breath, swollen breasts, short-windedness, indigestion, flatulence, jaundice, dropsy, gout, bladder infections, kidney stones, fever, dog bites, and infestation with lice or fleas. Additionally, in many times and places, alcohol was one of the few safe things to drink. Water contamination is a very old problem.

Some words for hangover, like ours, refer prosaically to the cause: the Egyptians say they are “still drunk,” the Japanese “two days drunk,” the Chinese “drunk overnight.” The Swedes get “smacked from behind.” But it is in languages that describe the effects rather than the cause that we begin to see real poetic power. Salvadorans wake up “made of rubber,” the French with a “wooden mouth” or a “hair ache.” The Germans and the Dutch say they have a “tomcat,” presumably wailing. The Poles, reportedly, experience a “howling of kittens.” My favorites are the Danes, who get “carpenters in the forehead.” In keeping with the saying about the Eskimos’ nine words for snow, the Ukrainians have several words for hangover. And, in keeping with the Jews-don’t-drink rule, Hebrew didn’t even have one word until recently. Then the experts at the Academy of the Hebrew Language, in Tel Aviv, decided that such a term was needed, so they made one up: hamarmoret, derived from the word for fermentation. (Hamarmoret echoes a usage of Jeremiah’s, in Lamentations 1:20, which the King James Bible translates as “My bowels are troubled.”) There is a biochemical basis for Jewish abstinence. Many Jews—fifty per cent, in one estimate—carry a variant gene for alcohol dehydrogenase. Therefore, they, like the East Asians, have a low tolerance for alcohol.

As for hangover remedies, they are legion. There are certain unifying themes, however. When you ask people, worldwide, how to deal with a hangover, their first answer is usually the hair of the dog. The old faithful in this category is the Bloody Mary, but books on curing hangovers—I have read three, and that does not exhaust the list—describe more elaborate potions, often said to have been invented in places like Cap d’Antibes by bartenders with names like Jean-Marc. An English manual, Andrew Irving’s “How to Cure a Hangover” (2004), devotes almost a hundred pages to hair-of-the-dog recipes, including the Suffering Bastard (gin, brandy, lime juice, bitters, and ginger ale); the Corpse Reviver (Pernod, champagne, and lemon juice); and the Thomas Abercrombie (two Alka-Seltzers dropped into a double shot of tequila). Kingsley Amis suggests taking Underberg bitters, a highly alcoholic digestive: “The resulting mild convulsions and cries of shock are well worth witnessing. But thereafter a comforting glow supervenes.” Many people, however, simply drink some more of what they had the night before. My Ukrainian informant described his morning-after protocol for a vodka hangover as follows: “two shots of vodka, then a cigarette, then another shot of vodka.” A Japanese source suggested wearing a sake-soaked surgical mask.

Application of the hair of the dog may sound like nothing more than a way of getting yourself drunk enough so that you don’t notice you have a hangover, but, according to Wayne Jones, of the Swedish National Laboratory of Forensic Medicine, the biochemistry is probably more complicated than that. Jones’s theory is that the liver, in processing alcohol, first addresses itself to ethanol, which is the alcohol proper, and then moves on to methanol, a secondary ingredient of many wines and spirits. Because methanol breaks down into formic acid, which is highly toxic, it is during this second stage that the hangover is most crushing. If at that point you pour in more alcohol, the body will switch back to ethanol processing. This will not eliminate the hangover—the methanol (indeed, more of it now) is still waiting for you round the bend—but it delays the worst symptoms. It may also mitigate them somewhat. On the other hand, you are drunk again, which may create difficulty about going to work.

As for the non-alcoholic means of combatting hangover, these fall into three categories: before or while drinking, before bed, and the next morning. Many people advise you to eat a heavy meal, with lots of protein and fats, before or while drinking. If you can’t do that, at least drink a glass of milk. In Africa, the same purpose is served by eating peanut butter. The other most frequent before-and-during recommendation is water, lots of it. Proponents of this strategy tell you to ask for a glass of water with every drink you order, and then make yourself chug-a-lug the water before addressing the drink.

A recently favored antidote, both in Asia and in the West, is sports drinks, taken either the morning after or, more commonly, at the party itself. A fast-moving bar drink these days is Red Bull, an energy drink, mixed with vodka or with the herbal liqueur Jägermeister. (The latter cocktail is a Jag-bomb.) Some people say that the Red Bull holds the hangover at bay, but apparently its primary effect is to blunt the depressive force of alcohol—no surprise, since an eight-ounce serving of Red Bull contains more caffeine than two cans of Coke. According to fans, you can rock all night. According to Maria Lucia Souza-Formigoni, a psychobiology researcher at the Federal University of São Paolo, that’s true, and dangerous. After a few drinks with Red Bull, you’re drunk but you don’t know it, and therefore you may engage in high-risk behaviors—driving, going home with a questionable companion—rather than passing out quietly in your chair. Red Bull’s manufacturers have criticized the methodology of Souza-Formigoni’s study and have pointed out that they never condoned mixing their product with alcohol.

When you get home, is there anything you can do before going to bed? Those still able to consider such a question are advised, again, to consume buckets of water, and also to take some Vitamin C. Koreans drink a bowl of water with honey, presumably to head off the hypoglycemia. Among the young, one damage-control measure is the ancient Roman method, induced vomiting. Nic van Oudtshoorn’s “The Hangover Handbook” (1997) thoughtfully provides a recipe for an emetic: mix mustard powder with water. If you have “bed spins,” sleep with one foot on the floor.

Now to the sorrows of the morning. The list-topping recommendation, apart from another go at the water cure, is the greasy-meal cure. (An American philosophy professor: “Have breakfast at Denny’s.” An English teen-ager: “Eat two McDonald’s hamburgers. They have a secret ingredient for hangovers.”) Spicy foods, especially Mexican, are popular, along with eggs, as in the Denny’s breakfast. Another egg-based cure is the prairie oyster, which involves vinegar, Worcestershire sauce, and a raw egg yolk to be consumed whole. Sugar, some say, should be reapplied. A reporter at the Times: “Drink a six-pack of Coke.” Others suggest fruit juice. In Scotland, there is a soft drink called Irn-Bru, described to me by a local as tasting like melted plastic. Irn-Bru is advertised to the Scots as “Your Other National Drink.” Also widely employed are milk-based drinks. Teen-agers recommend milkshakes and smoothies. My contact in Calcutta said buttermilk. “You can also pour it over your head,” he added. “Very soothing.”

Elsewhere on the international front, many people in Asia and the Near East take strong tea. The Italians and the French prefer strong coffee. (Italian informant: add lemon. French informant: add salt. Alcohol researchers: stay away from coffee—it’s a diuretic and will make you more dehydrated.) Germans eat pickled herring; the Japanese turn to pickled plums; the Vietnamese drink a wax-gourd juice. Moroccans say to chew cumin seeds; Andeans, coca leaves. Russians swear by pickle brine. An ex-Soviet ballet dancer told me, “Pickle juice or a shot of vodka or pickle juice with a shot of vodka.”

Many folk cures for hangovers are soups: menudo in Mexico, mondongo in Puerto Rico, işkembe çorbasi in Turkey, patsa in Greece, khashi in Georgia. The fact that all of the above involve tripe may mean something. Hungarians favor a concoction of cabbage and smoked meats, sometimes forthrightly called “hangover soup.” The Russians’ morning-after soup, solyanka, is, of course, made with pickle juice. The Japanese have traditionally relied on miso soup, though a while ago there was a fashion for a vegetable soup invented and marketed by one Kazu Tateishi, who claimed that it cured cancer as well as hangovers.

I read this list of food cures to Manuela Neuman, a Canadian researcher on alcohol-induced liver damage, and she laughed at only one, the six-pack of Coke. Many of the cures probably work, she said, on the same distraction principle as the hair of the dog: “Take the spicy foods, for example. They divert the body’s attention away from coping with the alcohol to coping with the spices, which are also a toxin. So you have new problems—with your stomach, with your esophagus, with your respiration—rather than the problem with the headache, or that you are going to the washroom every five minutes.” The high-fat and high-protein meals operate in the same way, she said. The body turns to the food and forgets about the alcohol for the time being, thus delaying the hangover and possibly alleviating it. As for the differences among the many food recommendations, Neuman said that any country’s hangover cure, like the rest of its cultural practices, is an adaptation to the environment. Chilies are readily available in Mexico, peanut butter in Africa. People use what they have. Neuman also pointed out that local cures will reflect the properties of local brews. If Russians favor pickle juice, they are probably right to, because their drink is vodka: “Vodka is a very pure alcohol. It doesn’t have the congeners that you find, for example, in whiskey in North America. The congeners are also toxic, independent of alcohol, and will have their own effects. With vodka you are just going to have pure-alcohol effects, and one of the most important of those is dehydration. The Russians drink a lot of water with their vodka, and that combats the dehydration. The pickle brine will have the same effect. It’s salty, so they’ll drink more water, and that’s what they need.”

Many hangover cures—the soups, the greasy breakfast—are comfort foods, and that, apart from any sworn-by ingredients, may be their chief therapeutic property, but some other remedies sound as though they were devised by the witches in “Macbeth.” Kingsley Amis recommended a mixture of Bovril and vodka. There is also a burnt-toast cure. Such items suggest that what some hungover people are seeking is not so much relief as atonement. The same can be said of certain non-food recommendations, such as exercise. One source says that you should do a forty-minute workout, another that you should run six miles—activities that may have little attraction for the hung over. Additional procedures said to be effective are an intravenous saline drip and kidney dialysis, which, apart from their lack of appeal, are not readily available.

There are other non-ingested remedies. Amazon will sell you a refrigeratable eye mask, an aromatherapy inhaler, and a vinyl statue of St. Vivian, said to be the patron saint of the hung over. She comes with a stand and a special prayer.

The most widely used over-the-counter remedy is no doubt aspirin. Advil, or ibuprofen, and Alka-Seltzer—there is a special formula for hangovers, Alka-Seltzer Wake-Up Call—are probably close runners-up. (Tylenol, or acetaminophen, should not be used, because alcohol increases its toxicity to the liver.) Also commonly recommended are Vitamin C and B-complex vitamins. But those are almost home remedies. In recent years, pharmaceutical companies have come up with more specialized formulas: Chaser, NoHang, BoozEase, PartySmart, Sob’r-K HangoverStopper, Hangover Prevention Formula, and so on. In some of these, such as Sob’r-K and Chaser, the primary ingredient is carbon, which, according to the manufacturers, soaks up toxins. Others are herbal compounds, featuring such ingredients as ginseng, milk thistle, borage, and extracts of prickly pear, artichoke, and guava leaf. These and other O.T.C. remedies aim to boost biochemicals that help the body deal with toxins. A few remedies have scientific backing. Manuela Neuman, in lab tests, found that milk-thistle extract, which is an ingredient in NoHang and Hangover Helper, does protect cells from damage by alcohol. A research team headed by Jeffrey Wiese, of Tulane University, tested prickly-pear extract, the key ingredient in Hangover Prevention Formula, on human subjects and found significant improvement with the nausea, dry mouth, and food aversion but not with other, more common symptoms, such as headache.

Five years ago, there was a flurry in the press over a new O.T.C. remedy called RU-21 (i.e., Are you twenty-one?). According to the reports, this wonder drug was the product of twenty-five years of painstaking research by the Russian Academy of Sciences, which developed it for K.G.B. agents who wanted to stay sober while getting their contacts drunk and prying information out of them. During the Cold War, we were told, the formula was a state secret, but in 1999 it was declassified. Now it was ours! “here’s one communist plot americans can really get behind,” the headline in the Washington Post said. “bottoms up to our buddies in russia,” the Cleveland Plain Dealer said. The literature on RU-21 was mysterious, however. If the formula was developed to keep your head clear, how come so many reports said that it didn’t suppress the effects of alcohol? Clearly, it couldn’t work both ways. When I put this question to Emil Chiaberi, a co-founder of RU-21’s manufacturer, Spirit Sciences, in California, he answered, “No, no, no. It is true that succinic acid”—a key ingredient of RU-21—“was tested at the Russian Academy of Sciences, including secret laboratories that worked for the K.G.B. But it didn’t do what they wanted. It didn’t keep people sober, and so it never made it with the K.G.B. men. Actually, it does improve your condition a little. In Russia, I’ve seen people falling under the table plenty of times—they drink differently over there—and if they took a few of these pills they were able to get up and walk around, and maybe have a couple more drinks. But no, what those scientists discovered, really by accident, was a way to prevent hangover.” (Like many other O.T.C. remedies, RU-21 is best taken before or while drinking, not the next morning.) Asians love the product, Chiaberi says. “It flies off the shelves there.” In the United States, it is big with the Hollywood set: “For every film festival—Sundance, the Toronto Film Festival—we get calls asking us to send them RU-21 for parties. So it has that glamour thing.”

Most cures for hangover—indeed, most statements about hangover—have not been tested. Jeffrey Wiese and his colleagues, in a 2000 article in Annals of Internal Medicine, reported that in the preceding thirty-five years more than forty-seven hundred articles on alcohol intoxication had been published, but that only a hundred and eight of these dealt with hangover. There may be more information on hangover cures in college newspapers—a rich source—than in the scientific literature. And the research that has been published is often weak. A team of scientists attempting to review the literature on hangover cures were able to assemble only fifteen articles, and then they had to throw out all but eight on methodological grounds. There have been more studies in recent years, but historically this is not a subject that has captured scientists’ hearts.

Which is curious, because anyone who discovered a widely effective hangover cure would make a great deal of money. Doing the research is hard, though. Lab tests with cell samples are relatively simple to conduct, as are tests with animals, some of which have been done. In one experiment, with a number of rats suffering from artificially induced hangovers, ninety per cent of the animals died, but in a group that was first given Vitamins B and C, together with cysteine, an amino acid contained in some O.T.C. remedies, there were no deaths. (Somehow this is not reassuring.) The acid test, however, is in clinical trials, with human beings, and these are complicated. Basically, what you have to do is give a group of people a lot to drink, apply the remedy in question, and then, the next morning, score them on a number of measures in comparison with people who consumed the same amount of alcohol without the remedy. But there are many factors that you have to control for: the sex of the subjects; their general health; their family history; their past experience with alcohol; the type of alcohol you give them; the amount of food and water they consume before, during, and after; and the circumstances under which they drink, among other variables. (Wiese and his colleagues, in their prickly-pear experiment, provided music so that the subjects could dance, as at a party.) Ideally, there should also be a large sample—many subjects.

All that costs money, and researchers do not pay out of pocket. They depend on funding institutions—typically, universities, government agencies, and foundations. With all those bodies, a grant has to be O.K.’d by an ethics committee, and such committees’ ethics may stop short of getting people drunk. For one thing, they are afraid that the subjects will hurt themselves. (All the studies I read specified that the subjects were sent home by taxi or limousine after their contribution to science.) Furthermore, many people believe that alcohol abusers should suffer the next morning—that this is a useful deterrent. Robert Lindsey, the president of the National Council on Alcoholism and Drug Dependence, told me that he wasn’t sure about that. His objection to hangover-cure research was simply that it was a misuse of resources: “Fifteen million people in this country are alcohol-dependent. That’s a staggering number! They need help: not with hangovers but with the cause of hangovers—alcohol addiction.” Robert Swift, an alcohol researcher who teaches at Brown University, counters that if scientists, through research, could provide the public with better information on the cognitive impairments involved in hangover, we might be able to prevent accidents. He compares the situation to the campaigns against distributing condoms, on the ground that this would increase promiscuity. In fact, the research has shown that free condoms did not have that effect. What they did was cut down on unwanted pregnancies and sexually transmitted disease.

Manufacturers of O.T.C. remedies are sensitive to the argument that they are enablers, and their literature often warns against heavy drinking. The message may be unashamedly mixed, however. The makers of NoHang, on their Web page, say what your mother would: “It is recommended that you drink moderately and responsibly.” At the same time, they tell you that with NoHang “you can drink the night away.” They list the different packages in which their product can be bought: the Bender (twelve tablets), the Party Animal (twenty-four), the It’s Noon Somewhere (forty-eight). Among the testimonials they publish is one by “Chad S,” from Chicago: “After getting torn up all day on Saturday, I woke up Sunday morning completely hangover-free. I must have had like twenty drinks.” Researchers address the moral issue less hypocritically. Wiese and his colleagues describe the damage done by hangovers—according to their figures, the cost to the U.S. economy, in absenteeism and poor job performance, is a hundred and forty-eight billion dollars a year (other estimates are far lower, but still substantial)—and they mention the tests with the airplane pilots, guaranteed to scare anyone. They also say that there is no experimental evidence indicating that hangover relief encourages further drinking. (Nor, they might have added, have there been any firm findings on this matter.) Manuela Neuman, more philosophically, says that some people, now and then, are going to drink too much, no matter what you tell them, and that we should try to relieve the suffering caused thereby. Such reasoning seems to have cut no ice with funding institutions. Of the meagre research I have read in support of various cures, all was paid for, at least in part, by pharmaceutical companies.

A truly successful hangover cure is probably going to be slow in coming. In the meantime, however, it is not easy to sympathize with the alcohol disciplinarians, so numerous, for example, in the United States. They seem to lack a sense of humor and, above all, the tragic sense of life. They appear not to know that many people have a lot that they’d like to forget. In the words of the English aphorist William Bolitho, “The shortest way out of Manchester is . . . a bottle of Gordon’s gin,” and if that relief is temporary the reformers would be hard put to offer a more lasting solution. Also questionable is the moral emphasis of the temperance folk, their belief that drinking is a lapse, a sin, as if getting to work on time, or living a hundred years, were the crown of life. They forget alcohol’s relationship to camaraderie, sharing, toasts. Those, too, are moral matters. Even hangovers are related to social comforts. Alcohol investigators describe the bad things that people do on the morning after. According to Genevieve Ames and her research team at the Prevention Research Center, in Berkeley, hungover assembly-line workers are more likely to be criticized by their supervisors, to have disagreements with their co-workers, and to feel lousy. Apart from telling us what we already know, such findings are incomplete, because they do not talk about the jokes around the water cooler—the fellowship, the badge of honor. Yes, there are safer ways of gaining honor, but how available are they to most people?

Outside the United States, there is less finger-wagging. British writers, if they recommend a cure, will occasionally say that it makes you feel good enough to go out and have another drink. They are also more likely to tell you about the health benefits of moderate drinking—how it lowers one’s risk of heart disease, Alzheimer’s, and so on. English fiction tends to portray drinking as a matter of getting through the day, often quite acceptably. In P. G. Wodehouse’s Jeeves and Wooster series, a hangover is the occasion of a happy event, Bertie’s hiring of Jeeves. Bertie, after “a late evening,” is lying on the couch in agony when Jeeves rings his doorbell. “ ‘I was sent by the agency, sir,’ he said. ‘I was given to understand that you required a valet.’ ” Bertie says he would have preferred a mortician. Jeeves takes one look at Bertie, brushes past him, and vanishes into the kitchen, from which he emerges a moment later with a glass on a tray. It contains a prairie oyster. Bertie continues, “I would have clutched at anything that looked like a life-line that morning. I swallowed the stuff. For a moment I felt as if somebody . . . was strolling down my throat with a lighted torch, and then everything seemed suddenly to get all right. The sun shone in through the window; birds twittered in the tree-tops; and, generally speaking, hope dawned once more. ‘You’re engaged,’ I said.” Here the hangover is a comedy, or at least a fact of life. So it has been, probably, since the Stone Age, and so it is likely to be for a while yet. ♦

Tuesday, February 22, 2011

How Alcohol ruins women's sleep

Why Booze Ruins Women's Sleep
by KATE DAILEY
from the Daily Beast

From disrupting sleep cycles to improving bone density, researchers are discovering that drinking affects women differently than men in all sorts of unexpected ways.

For the sleep deprived, alcohol is a fickle mistress. A glass of wine may help you go down for the night, but a few too many can send your sleep cycle into a tailspin. But until very recently, what no one knew was that for women, this is particularly true. It's just one more way in which scientists say alcohol affects women differently than men.

The study, published in the journal Alcoholism: Clinical & Experimental Research indicates that women's sleep is more easily disrupted by alcohol than men's. Ninety-three subjects were given either a placebo or enough alcohol so that their BAL was .11 (most states consider .08 to be legally impaired), then monitored as they slept. Women reported feeling more tired before they went to bed than men did, and woke up more often during the night and stayed awake for more minutes, says Damaris J. Rohsenow, Ph.D., one of the study's authors. Interestingly, the women did not report feeling sleepier than the men did after their night of tossing and turning. "They had worse sleep quality, but didn't notice," says Rohsenow, an associate director at the Center for Alcohol and Addiction Studies at Brown University. (The mechanism for why women had more disrupted sleep than men did was not explained.)

Until 15 years ago, very little research had been done on women's response to alcohol, says Elizabeth Epstein, Ph.D. a research professor for the Center of Alcohol Studies at Rutgers. Prior to that, our understanding of how humans processed alcohol—and how we dealt with any subsequent addiction issues—was based on research in men. That was the case for most medical inquiries, which often limited their studies to male subjects both out of centuries-long habit and because women, with their pesky hormones, were viewed as liable to skew study results. At some point, however, the medical community started to realize that the response of half their patients might not be skewed, but significant, and integral to understanding successful treatment options.

When scientists did eventually begin to delve into the differences between men and women when it comes to drinking, they found some interesting differences. First, even when a man and a woman weigh exactly the same amount, a woman only needs 90 percent of what a man consumes to achieve the same blood alcohol level. (How drunk the woman will feel compared to the man depends on her individual tolerance.) The exact reason why this happens is unknown, but it may be because women have less body water. Women also have significantly fewer stomach enzymes that facilitate the breakdown of alcohol than men, which means that "more unmetabolized pure ethanol is going into the organs," says Epstein. "For women, since there's less being metabolized, more alcohol is directly affecting the liver, heart, brain, and intestines." Female alcoholics often start drinking later in life than men, but because of this phenomenon, known as the "telescoping effect," these women often show comparable organ damage to male alcoholics who have been drinking much longer.

Coincidentally, a second study released this week in the European Journal of Clinical Nutrition found that alcohol consumption later in life can have a protective effect on bone density—but what type of alcohol was beneficial depended on one's gender. This is particularly compelling news for women, who lose bone density faster than men do. The researchers followed 862 subjects, all over 50, for two years. They found that in men, drinking red wine correlated with less bone loss, and frequent liquor and spirits consumption was connected with more. Women, however, showed none of these effects. But what women did see was a positive correlation between drinking and bone density if they consumed low-alcohol beer. In this study, quantity may have played a role: red wine is associated with moderate drinking, while liquor and spirits are correlated with heavier drinking.

When it comes to the psychology of drinking and gender, there is much more research. In those cases, however, it's difficult to parse how much of the findings are based on the physiology and brain chemistry versus how many are rooted in external cues. For instance, one study found that after experiencing a stressful or upsetting event, men were more likely to crave alcohol, while women were more likely to report feeling depressed or anxious. "There are certain neural circuitry that are associated with stress and neural circuitry associated with reward…and they might be more closely linked in men," says study author Tara Chaplin Ph.D., an assistant professor of psychiatry at the Yale school of medicine. On the other hand, "It could also be connected to social pressures that girls and women feel—it's more acceptable to cry or feel anxious about things. Men might be pressured to minimize, so perhaps they turn to drinking."

In her studies of problem drinkers, however, Epstein found that too much depression and anxiety can lead women to alcoholism, while men were triggered by specific stressful incidents, like the loss of a job. She also found that while women respond better to single-sex group therapy and team treatment approaches then men do, women are much less likely to seek help. "They have barriers to treatment that men don't have—childcare, fear of losing their children, and women on the whole are less likely to have medical insurance," she says.

There's still a lot scientists don't understand about alcohol (though Rohsenow and her colleagues found that there's no difference in drunkenness between dark and light liquors, no matter what your mother told you). And there's even less that they understand about how booze breaks down in men vs. women. But the one tried and true rule of drinking was further confirmed by the participants in the sleep study, and it didn't matter whether they were male or female—every subject who'd been given the alcohol reported feeling lousy the next day.

Wednesday, November 10, 2010

More Art: Giant drunken monkey made of flip fops

Go to Geekologie.com or Zeutch.com for lots more pics!



From Geekologie:
This is a giant passed-out monkey sculpture made out of flip-flops in São Paulo, Brazil, to celebrate Pixel Show, an international art and design conference. Because if there are two things that go hand in hand in this world, it's drunk monkeys and art.


Thursday, October 28, 2010

The Worst Science Jobs 2010

As a side note - I am a shit-stirrer by trade, and its really not that bad ;P and the last job seems awesome! To see a list from 2009 - check out this old post -MA

From io9.com
by ANNALEE NEWITZ
Fart collecting and testicle mashing: The grossest jobs in science

Fart collecting and testicle mashing: The grossest jobs in science Considering a career in science? You know, all those clean labs and shiny white coats? Well consider this: A lot of science jobs are more disgusting than all the Saw movies put together. We round up seven of the grossest.

Beetle testicle crusher
Do the size of your balls help you find a mate? To answer this burning question, a group of researchers in Japan set out to study whether big-balled beetles scored more with the ladies than small-balled beetles. To do this, I'm afraid, they sacrificed a lot of beetle balls. And to measure their size and volume, they had to grind up their little sacs and measure the volume of each one. The good news is that you don't need big balls to enjoy reproductive success in the beetle world. The bad news is that there are some really sad beetles limping around the lab right now.

Corpse grinder
Sometimes forensic scientists have to analyze corpses after they've been buried. In cases where they are trying to identify the person buried, or do toxicology studies (to see if the person may have been poisoned, for example), they need to get samples of the dead person's DNA. So they exhume the body, take chunks of bone or tissue, grind it up, filter out the DNA, and sequence as much of it as they need to for their research. It's just like that famous cult movie Corpse Grinders, except without the cat food thing.

Whale snot collector
One of this year's IgNobel Prizes for weird science went to three biologists who spent so much time collecting whale snot (to study disease patterns) that they actually invented a special remote-controlled helicopter to scoop up the goo for them. Not only do these brave researchers spend their days sifting through giant whale boogers, but now they have a robot slave to help out. Extra points for evil minionage!
Shit-stirrer
Many studies have been done on the microbes that live in animal guts, from mice to humans. Before scientists get to play around with their fancy DNA sequencers, somebody has to collect what once research team delicately referred to as "freshly voided fecal matter." And then they have to put that steaming poop into a special solution and shake it up. That's right - in labs all over the world, there are genomics and proteomics researchers who are shaking up giant bottles full of poop.

Bacteria chaser
Although bacteria may be the most awesomely adaptable creatures on the planet, they aren't exactly easy on the nose. In fact, scientists who study extremophiles - microbes that live in highly acidic areas, or in regions of intense heat or cold - often have to gather their samples in areas that smell hideous and are intensely hot. It's a stinky job, but somebody has to do it.

Fart statistician
How do you know when you fart too much? Because gastroenterologists have studied human fart production, figured out what the average number of daily farts should be, and determined that levels above that might indicate a medical problem. All hail the fart counters, who are keeping our gastrointestinal tracts healthy. And because I know you want to know: The mean number of farts in humans is "13.6 episodes per day," according to one expert.

Drunken hookup data analyst
Is it true that people look more attractive after you've tossed back a couple of drinks? To find out, a group of long-suffering researchers had to ask drunk people in bars who they would hit. These social scientists endured the real-life version of reading comment threads on YouTube, and discovered - not surprisingly - that people get more attractive the more obnoxiously wasted you get.

Saturday, June 19, 2010

Nicholas D Kristof OpEd on African parents prioritizing boozing over their children's education


A plea for microfinance in subsaharan Africa: Although its uncomfortable to admit, this is happening in some of the poorest parts of Africa, parents (predominantly fathers) prioritize booze/cigs/petits nanas over their children's education. A really great NYtime OpEd report by Nicholas D Kristof.

I can't embed the vid so you can go to Nicholas D Kristof's facebook page to view the video (or the DNApes facebook page) or watch it on the NYTimes Website

Saturday, May 22, 2010

looking at uncomfortable truths for poverty alleviation

From the NYTimes.com
Moonshine or the Kids?
By NICHOLAS D. KRISTOF

There’s an ugly secret of global poverty, one rarely acknowledged by aid groups or U.N. reports. It’s a blunt truth that is politically incorrect, heartbreaking, frustrating and ubiquitous:

It’s that if the poorest families spent as much money educating their children as they do on wine, cigarettes and prostitutes, their children’s prospects would be transformed. Much suffering is caused not only by low incomes, but also by shortsighted private spending decisions by heads of households.

That probably sounds sanctimonious, haughty and callous, but it’s been on my mind while traveling through central Africa with a college student on my annual win-a-trip journey. Here in this Congolese village of Mont-Belo, we met a bright fourth grader, Jovali Obamza, who is about to be expelled from school because his family is three months behind in paying fees. (In theory, public school is free in the Congo Republic. In fact, every single school we visited charges fees.)

We asked to see Jovali’s parents. The dad, Georges Obamza, who weaves straw stools that he sells for $1 each, is unmistakably very poor. He said that the family is eight months behind on its $6-a-month rent and is in danger of being evicted, with nowhere to go.

The Obamzas have no mosquito net, even though they have already lost two of their eight children to malaria. They say they just can’t afford the $6 cost of a net. Nor can they afford the $2.50-a-month tuition for each of their three school-age kids.

“It’s hard to get the money to send the kids to school,” Mr. Obamza explained, a bit embarrassed.

But Mr. Obamza and his wife, Valerie, do have cellphones and say they spend a combined $10 a month on call time.

In addition, Mr. Obamza goes drinking several times a week at a village bar, spending about $1 an evening on moonshine. By his calculation, that adds up to about $12 a month — almost as much as the family rent and school fees combined.

I asked Mr. Obamza why he prioritizes alcohol over educating his kids. He looked pained.

Other villagers said that Mr. Obamza drinks less than the average man in the village (women drink far less). Many other men drink every evening, they said, and also spend money on cigarettes.

“If possible, I drink every day,” Fulbert Mfouna, a 43-year-old whose children have also had to drop out or repeat grades for lack of school fees, said forthrightly. His eldest son, Jude, is still in first grade after repeating for five years because of nonpayment of fees. Meanwhile, Mr. Mfouna acknowledged spending $2 a day on alcohol and cigarettes.

Traditionally, a young man here might have paid his wife’s family a “bride price” of a pair of goats. Now the “bride price” starts with oversized jugs of wine and two bottles of whiskey.

Two M.I.T. economists, Abhijit Banerjee and Esther Duflo, found that the world’s poor typically spend about 2 percent of their income educating their children, and often larger percentages on alcohol and tobacco: 4 percent in rural Papua New Guinea, 6 percent in Indonesia, 8 percent in Mexico. The indigent also spend significant sums on soft drinks, prostitution and extravagant festivals.

Look, I don’t want to be an unctuous party-pooper. But I’ve seen too many children dying of malaria for want of a bed net that the father tells me is unaffordable, even as he spends larger sums on liquor. If we want Mr. Obamza’s children to get an education and sleep under a bed net — well, the simplest option is for their dad to spend fewer evenings in the bar.

Because there’s mounting evidence that mothers are more likely than fathers to spend money educating their kids, one solution is to give women more control over purse strings and more legal title to assets. Some aid groups and U.N. agencies are working on that.

Another approach is microsavings, helping poor people save money when banks aren’t interested in them. It’s becoming increasingly clear that the most powerful part of microfinance isn’t microlending but microsavings.

Microsavings programs, organized by CARE and other organizations, work to turn a consumption culture into a savings culture. The programs often keep household savings in the women’s names, to give mothers more say in spending decisions, and I’ve seen them work in Africa, Latin America and Asia.

Well-meaning humanitarians sometimes burnish suffering to make it seem more virtuous and noble than it often is. If we’re going to make more progress, and get kids like the Obamza children in school and under bed nets, we need to look unflinchingly at uncomfortable truths — and then try to redirect the family money now spent on wine and prostitution.

Tuesday, March 9, 2010

Women Who Drink Gain Less Weight

From the New York Times
By TARA PARKER-POPE

Dieters are often advised to stop drinking alcohol to avoid the extra calories lurking in a glass of wine or a favorite cocktail. But new research suggests that women who regularly consume moderate amounts of alcohol are less likely to gain weight than nondrinkers and are at lower risk for obesity.

The findings, reported this week in the Archives of Internal Medicine, are based on a study of 19,220 United States women aged 39 or older who fall into the “normal weight” category based on their body mass index. Researchers at Brigham and Women’s Hospital in Boston tracked the women’s drinking habits over 13 years. About 60 percent of the women were light or regular drinkers, while about 40 percent reported drinking no alcohol.

Over the course of the study, 41 percent of the women became overweight or obese. Although alcohol is packed with calories (about 150 in a six-ounce glass of wine), the nondrinkers in the study actually gained more weight over time: nine pounds, on average, compared with an average gain of about three pounds among regular moderate drinkers. The risk of becoming overweight was almost 30 percent lower for women who consumed one or two alcohol beverages a day, compared with nondrinkers.

The findings are certain to be confusing for women who continue to receive conflicting messages about the health benefits and risks of alcohol. Although moderate drinking is associated with better heart health, regular drinking also increases breast cancer risk.

The trend toward less weight gain among drinkers doesn’t appear to hold true for men. A 2003 study of British men showed that regular drinkers gained more weight than nondrinkers. Studies suggest that drinking alcohol has different effects on eating habits among men and women. Men typically add alcohol to their daily caloric intake, whereas women are more likely to substitute alcohol for food. In the Archives study, women who drank alcohol reported fewer calories from food sources, particularly carbohydrates.

In addition, there may be differences in how men and women metabolize alcohol. Metabolic studies show that after men drink alcohol, they experience little if any metabolic change. But alcohol appears to slightly speed up a woman’s metabolism.

The link between consumption of red wine and less weight gain was particularly pronounced in the Archives study. Some studies have suggested that resveratrol, a compound present in grapes and red wine, appears to inhibit the development of fat cells and to have other antiobesity properties.

The findings don’t mean women should rush to drink alcohol to lose weight. Other research shows that once a person is already overweight, her alcohol metabolism is more efficient, and so an overweight woman may gain more weight from alcohol than a lean woman. The data do, however, suggest that for many women facing weight problems, the extra calories are probably not coming from alcoholic beverages.


Thanks to Linda V for the link!

Tuesday, January 27, 2009

"Wild living" alocholic Vervet Monkeys



A video from the BBC's "Weird Nature" series of "wild living", vervet monkeys from St. Kitts that perform daily raids on the island's bars. Parallels between human drinking habits (and actions) are discussed.